pentobarbital will reduce the extent or result of trazodone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lower the level or impact of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lessen the extent or influence of naloxegol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Usage of naloxegol with potent CYP3A4 inducers is not advisable
pentobarbital will lessen the level or outcome of alprazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will decrease the level or outcome of etravirine by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Observe.
pentobarbital will lower the extent or result of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. The efficacy of hormonal contraceptives might be reduced. Utilization of a nonhormonal contraceptive is recommended.
Contraindicated (one)pentobarbital will minimize the level or influence of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers may result in reduced serum concentrations and lack of antimalarial efficacy
pentobarbital boosts toxicity of methoxyflurane by escalating metabolism. Contraindicated. Enhanced metabolism of methoxyflurane to nephrotoxic compounds.
buprenorphine, prolonged-acting injection and pentobarbital the two improve sedation. Avoid or Use Alternate Drug. Limit use to sufferers for whom choice remedy options are insufficient
Comment: Barbiturates could enhance adverse effects, like respiratory depression, made by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates improve metabolism and reduce blood concentrations of TCAs.
pentobarbital will decrease the level or effect of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.
pentobarbital will lessen the level or result of atorvastatin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will decrease the extent or result of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use check here Alternate Drug. Result of coadministering a powerful CYP3A4 inducer with fedratinib has not been researched.
pentobarbital will lessen the extent or result of vinorelbine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Not known.